Photodynamic Therapy – UPMC

Photodynamic Therapy (PDT) is an advanced, non-invasive dermatological treatment used to treat a variety of skin conditions and cosmetic skin concerns. It does not require systemic medications; instead, it works locally through the application of a photosensitizing agent to the affected skin area, followed by exposure to a specific light source. The light activates oxidative reactions that repair or destroy damaged cells. PDT is an effective alternative to more invasive treatments and is associated with a low risk of side effects.

Book an Appointment at UPMC

Photodynamic Therapy is available at:

• UPMC Salvator Mundi International Hospital

How It Works

A photosensitizing agent is applied to the affected skin lesion. After an incubation period, the area is exposed to a specific wavelength of light. The light activates the photosensitizer, triggering oxidative reactions within damaged cells that either repair or destroy them. This controlled and localized process minimizes damage to the surrounding healthy tissue.

Therapeutic Indications

Photodynamic Therapy may be used for:

• Superficial Skin Cancers – Early-stage squamous cell carcinoma and basal cell carcinoma.
• Actinic Keratoses – Precancerous lesions caused by chronic sun exposure.
• Porokeratosis – A rare skin disorder with potential for malignant transformation.
• Photoaging – Skin rejuvenation and improvement of skin texture and appearance caused by sun-induced aging.
• Scleroderma – In selected localized subtypes of the disease.

Benefits

Photodynamic Therapy offers several advantages, including effectiveness in treating a wide range of skin conditions, a low risk of side effects, excellent cosmetic outcomes, no need for general anesthesia, rapid recovery, and the ability to treat large areas of skin with minimal scarring.